RESUMO
The development of vaccines that could provide broad protection against antigenically variant influenza viruses has long been the ultimate prize in influenza research. Recent developments have pushed us closer to this goal, and such vaccines may now be within reach. This brief review outlines the current approaches to broadly protective vaccines, and the probable hurdles and roadblocks to achieving this goal.
Assuntos
Hemaglutininas/imunologia , Vacinas Virais/imunologia , Adjuvantes Farmacêuticos , Administração Intranasal , Antígenos CD4/imunologia , Antígenos CD8/imunologia , Hemaglutinação/imunologia , Humanos , Neuraminidase/imunologia , Proteínas do Envelope Viral/imunologiaRESUMO
The development of vaccines that could provide broad protection against antigenically variant influenza viruses has long been the ultimate prize in influenza research. Recent developments have pushed us closer to this goal, and such vaccines may now be within reach. This brief review outlines the current approaches to broadly protective vaccines, and the probable hurdles and roadblocks to achieving this goal.
